Injured in an out-of-town college basketball game, Matt and his teammates end up in the local hospital. In traction and unable to move, Matt begins to see things get more and more bizarre at the hospital. Sweet young candy stripers seem to be changing in front of his eyes. When they begin seducing all the men in the hospital and wrapping them up in a hideous weblike substance, Matt realizes that he has to get out. Dragging his unwilling friends along with him, Matt leads his friends in a life and death struggle that becomes the biggest fight of his life.